研究方向

1. 种子生物学； 2. 细胞信号转导

学习、工作经历

2013.07 - 至今 ky开云手机版，历任讲师、副教授、教授

2008.09 - 2013.07 清华大学生命科学ky开云（中国），获理学博士学位

2012.10 - 2012.12 比利时鲁汶大学 (KU Leuven) 医ky开云（中国），访学　

2004.09 - 2008.07 西安交通大学生命科学与技术ky开云（中国），获生物工程、英语双学士学位

承担项目

1. 国家重点研发计划子课题，2023YFD2200605-3，油松种子园丰产稳产高效技术体系研建与示范，2023/12-2028/11，在研，主持

2. 国家自然科学基金面上项目，31971646，金属离子与金属硫蛋白在PEG诱导的柠条种子脱水耐性重建中的作用，2020/01-2023/12，在研，主持

3. 北京林业大学科技创新计划项目（自由探索），2019ZY26，家榆种子衰老相关miRNA的鉴定及调控机制研究，2019/04-2020/12，已结题，主持

4. 国家自然科学基金青年科学基金项目，31501144，RACK1调控Dishevelled蛋白和Wnt信号的分子机制与生理意义研究，2016/01-2018/12，已结题，主持

5. 北京林业大学新进教师科研启动基金项目，BLX2013023，家榆种子人工老化诱发程序性细胞死亡的转录组分析，2013/07-2015/07，已结题，主持

代表性论著

1. Ying Li^#*, Yu Wang^#, Yuqi He, Xu Huang, Tiantian Ye, Hao Wu, Tianxiao Ma, Hugh W. Pritchard, Xiaofeng Wang^*, Hua Xue^* (2024) Glutathionylation of a glycolytic enzyme promotes cell death and vigor loss during aging of elm seeds. Plant Physiology, https://doi.org/10.1093/plphys/kiae197.

2. Meiyan Zeng^#, Yuqi He^#, Xue Gao, Yu Wang, Shiming Deng, Tiantian Ye, Xiaofeng Wang, Hua Xue^* (2021) Characteristics and functions of glyceraldehyde 3-phosphate dehydrogenase S-nitrosylation during controlled aging of elm and Arabidopsis seeds. Journal of Experimental Botany, 72(20): 7020-7034.

3. Yuqi He^#, Hua Xue^#, Ying Li, Xiaofeng Wang^* (2018) Nitric oxide alleviates cell death through protein S-nitrosylation and transcriptional regulation during the ageing of elm seeds. Journal of Experimental Botany, 69(21): 5141-5155.

4. Minzhang Cheng^#, Hua Xue^#, Weipeng Cao^#, Wenxia Li, Hua Chen, Bofeng Liu, Ye-Guang Chen^* (2016) Rack1 promotes dishevelled degradation via autophagy and antagonizes Wnt signaling. Journal of Biological Chemistry, 291(24):12871-12879.

5. Hua Xue^#, Zhicheng Xiao^#, Jing Zhang, Jun Wen, Yuan Wang, Zai Chang, Jing Zhao, Xiang Gao, Jie Du^*, Ye-Guang Chen^* (2013) Disruption of Dapper3 gene aggravates ureteral obstruction-mediated renal fibrosis by amplifying Wnt/β-catenin signaling. Journal of Biological Chemistry, 288: 15006-15014.

其他论著

1. Tiantian Ye^#, Tianxiao Ma^#, Yang Chen^#, Chang Liu, Zhiyuan Jiao, Xiaofeng Wang, Hua Xue^* (2024) The role of redox-active small molecules and oxidative protein post-translational modifications in seed aging. Plant Physiology and Biochemistry, 213: 108810.

2. Ying Li^#, Chang Liu^#, Manyao Qi^#, Tiantian Ye, Ying Kang, Yu Wang, Xiaofeng Wang, Hua Xue^* (2023) Effect of the metal ion-induced carbonylation modification of mitochondrial membrane channel protein VDAC on cell vitality, seedling growth and seed aging. Frontiers in Plant Science, 14: 1138781.

3. Tiantian Ye^#, Xu Huang^#, Tianxiao Ma^#, Ying Li, Xiaofeng Wang, Hai Lu, Hua Xue^* (2023) Integrated analysis of miRNAome and transcriptome identify regulators of elm seed aging. Plants, 12(8): 1719.

4. Long Peng, Xu Huang, Manyao Qi, Hugh W. Pritchard, Hua Xue^* (2022) Mechanistic insights derived from re-establishment of desiccation tolerance in germinating xerophytic seeds: Caragana korshinskii as an example. Frontiers in Plant Science, 13: 1029997.

5. Long Peng^#, Hao Wu^#, Huang Xu^#, Meiyan Zeng, Shiming Deng, Hua Xue^*, Xiaofeng Wang^* (2021) Functional characterization of an unobtrusive protein, CkMT4, in re-establishing desiccation tolerance in germinating seeds. International Journal of Biological Macromolecules, 173: 180-192.

6. Shiming Deng, Zhijun Deng, Xiaofeng Wang, Hai Lu, Hua Xue^* (2021) Effects of temperature, scarification, stratification, phytohormones, and after-ripening on the dormancy and germination of Eucommia ulmoides Oliv. seeds. Forests, 12(11): 1593.

7. Long Peng, Qi Sun, Hua Xue^*, Xiaofeng Wang^* (2018) iTRAQ-based quantitative proteomic analysis reveals pathways associated with re-establishing desiccation tolerance in germinating seeds of Caragana korshinskii Kom. Journal of Proteomics, 179: 1-16.

8. Yin Jing^#, Sirui Lang^#, Dongmei Wang, Hua Xue^*, Xiaofeng Wang^* (2018) Functional characterization of galactinol synthase and raffinose synthase in desiccation tolerance acquisition in developing Arabidopsis seeds. Journal of Plant Physiology, 230: 109-121.

9. Liqiang Su, Jiaguo Li, Hua Xue^*, Xiaofeng Wang^* (2017) Super absorbent polymer seed coatings promote seed germination and seedling growth of Caragana korshinskii in drought. Journal of Zhejiang University-Science B, 18(8): 696-706.

10. Liqiang Su, Qinying Lan, Hugh W. Pritchard, Hua Xue^* and Xiaofeng Wang^* (2016) Reactive oxygen species induced by cold stratification promote germination of hedysarum scoparium seeds. Plant Physiology and Biochemistry, 109: 406-415.

11. Yu Wang^#, Ying Li^#, Hua Xue, Hugh W. Pritchard and Xiaofeng Wang^* (2015) Reactive oxygen species (ROS)-provoked mitochondria-dependent cell death during ageing of elm (Ulmus pumila L.) seeds. The Plant Journal, 81: 438-452.

12. 曾玫艳, 李莹, 汪晓峰, 薛华^* (2024). 人工老化和自然老化家榆种子的iTRAQ蛋白质组学分析. 分子植物育种, 22(3): 761-769.

13. 康瑛, 齐曼瑶, 刘畅, 赵俊岩, 孙琪, 王腾翔, 汪晓峰, 薛华^* (2022). 柠条种子脱水耐性重建的脂质组分析. 分子植物育种, https://kns.cnki.net/kcms/detail/46.1068.S.20220816.1509.002.html.

14. 田知秋, 洪汉辉, 康向阳, 汪晓峰^*, 薛华 (2019). 插穗年龄对毛白杨不定根形成影响的转录组分析. 植物学研究, 8(3): 293-306.

教材与教学论文

1. 汪晓峰, 薛华, 沈昕. 分子生物学实验技术[M]. 北京: 中国林业出版社, 2017. （国家林业局研究生教育“十三五”规划教材）

2. 陆海, 薛华, 沈昕, 饶国栋. 分子生物学实验技术（第2版）[M]. 北京: 中国林业出版社. （国家林业局研究生教育“十四五”规划教材，2021年立项）

3. 薛华, 杨海灵, 汪晓峰. “生物化学A”课程浸入式教学的实践探索——以北京林业大学为例[J]. 中国林业教育, 2023, 41(03): 75-78.

4. 薛华, 汪晓峰. “生物化学实验”课程数字化教学模式初探[J]. 中国林业教育. 2017, 35(S1): 55-57.

5. 薛华, 汪晓峰. “生物化学实验”课程的发展现状与改进思路[A]. //于志明. 秉烛者的思考与实践(2015)北京林业大学教育教学改革优秀论文选编[C]. 北京：中国林业出版社. 2015, 279-282.

6. 薛华, 汪晓峰. 大学生科研训练的现状及改进的几点建议[A]. //于志明. 秉烛者的思考与实践(2014)北京林业大学教育教学改革优秀论文选编[C]. 北京：中国林业出版社. 2014, 252-254.

获奖情况

1. 北京林业大学优秀共青团干部，2024

2. 北京林业大学教育教学改革与研究优秀论文奖，三等奖，2023

3. 北京林业大学党员先锋岗，2022

4. 北京林业大学优秀硕士学位论文指导教师，2021

5. 傅家瑞青年种子生物学优秀研究论文，二等奖，第七届全国种子科学与技术学术研讨会，2021

6. 北京林业大学本科课程优秀教案，优秀奖，2020

7. 傅家瑞青年种子生物学优秀研究论文，三等奖，第六届全国种子科学与技术学术研讨会，2019

8. 北京林业大学优秀班主任，2018、2019