Extraction condition optimization, quantitative analysis and anti-diabetes bioactivities evaluation of acorn polysaccharides from three different species. Food Chemistry: X, 2024.

Evaluation of the Protective Bioactivity and Molecular Mechanism Verification of Lactoferrin in an Alzheimer's Mouse Model with Ulcerative Enteritis. Journal of Dairy Science, 2024.

The alleviative effects comparison of four flavonoids from bamboo leaves on ulcerative colitis in an Alzheimer mouse model. CNS Neuroscience & Therapeutics, 2024.

Circadian rhythm disruption leads to the progression of Alzheimer's disease through regulating m6A methylation of key gene Hif3α. CNS Neuroscience & Therapeutics, 2024.

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments. Chinese Medicine, 2023.

Anthracycline Chemicals with an-Thracyclinone Structure Exert Antitumor Effects by Inhibiting Angiogenesis and Lymphangiogenesis in A Xenografted Gastric Tumor Model. Gastric Cancer, 2023.

Lactoferrin suppresses the progression of colon cancer under hyperglycemia by targeting WTAP/m6A/NT5DC3/HKDC1 axis. Journal of Translational Medicine, 2023.
Milk Active Ingredients, 2 ‘-fucosyllactose Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells in vitro. Foods, 2022.

Lactoferrin inhibits the development of T2D to colon tumors by regulating NT5DC3/PI3K/AKT/mTOR signaling pathway. Foods, 2022.

Dynamic Regulation of eEF1A1 Acetylation Affects Colorectal Carcinogenesis. Biological Chemistry, 2022.

Single-cell RNA-sequencing uncovers compound kushen injection synergistically improves the efficacy of chemotherapy by modulating the tumor environment of breast cancer. Frontiers in Immunology, 2022.

Lactoferrin Alleviates Lipopolysaccharide-induced Infantile Intestinal Immune Barrier Damage By Regulating ELAVL1-related Signaling Pathway. International Journal of Molecular Sciences, 2022.

2’-Fucosyllactose Suppresses Angiogenesis and Alleviates Toxic Effects of 5-Fu in a HCT116 Colon Tumor-Bearing Model. Molecules, 2022.

2’-fucosyllactose Ameliorates Inflammatory Bowel Disease by Modulating Gut Microbiota and Promoting MUC2 Expression. Frontiers in Nutrition, 2022.

Protective effects of recombinant lactoferrin with different iron saturations on enteritis injury in young mice. Journal of Dairy Science, 2022.

Baicalin suppresses the progression of Type II diabetes-induced liver tumor through regulating METTL3/m6A/HKDC1 axis and downstream p-JAK2/STAT1/clevaged Caspase3 pathway. PHYTOmedicine, 2021.

Alkaline phosphatase attenuates LPS-induced liver injury by regulating the miR-146a-related inflammatory pathway. International Immunopharmacology, 2021.

The crosstalking between gut microbiome and immune response regulated by diet nutrients in inflammatory bowel disease. Foods, 2021.

Lactoferrin could alleviate liver injury caused by Maillard reaction products with furan ring through regulating necroptosis pathway. Food Science & Nutrition, 2021.

The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway. Peer J, 2021.

Inhibitory effect of lactoferrin on pulmonary inflammatory process induced by lipopolysaccharide through modulating TLR4-related pathway. Journal of Dairy Science, 2021.

Angustoline Inhibited Esophageal Tumors Through Regulating LKB1/AMPK/ELAVL1/LPACT2 Pathway And Phospholipid Remodeling. Frontiers in Oncology, 2020.

Maillard reaction products with furan ring, like furosine, cause kidney injury through triggering ferroptosis pathway. Food Chemistry, 2020.

Investigation and comparison of the protective activities of three functional proteins-lactoferrin, α-lactalbumin, and β-lactoglobulin in cerebral ischemia reperfusion injury. Journal of Dairy Science, 2020.

The combination of two bioactive constituents, lactoferrin and linolenic acid, inhibits mouse xenograft esophageal tumor growth by downregulating lithocholyltaurine and inhibiting the JAK2/STAT3-related pathway. ACS Omega, 2020.

Toxic effects of furosine by oral intake on liver and kidney and toxicokinetics research in mice acute toxicity model. Food Science and Technology Science, 2020.

Modulation activity of heat-treated and untreated lactoferrin on the TLR-4 pathway in anoxia cell model and cerebral ischemia reperfusion mouse model. Journal of Dairy Science, 2019.

Furosine, a Maillard Reaction Product, Triggers Necroptosis in Hepatocytes by Regulating the RIPK1/RIPK3/MLKL Pathway. International Journal of Molecular Sciences, 2019.

Investigation and comparison of the anti-tumor activities of lactoferrin, α-lactalbumin and β-lactoglobulin, in A549/HT29/HepG2/MDA231-LM2 tumor models. Journal of Dairy Science, 2019.

L-proline alleviates kidney injury caused by AFB1 and AFM1 through regulating excessive apoptosis of kidney cells. Toxins, 2019.

Lactoferrin induces the synthesis of vitamin B6 and protects HUVEC functions by activating PDXP and the PI3K/AKT/ERK1/2 pathway. International Journal of Molecular Sciences, 2019.

Furosine Posed Toxic Effects on Primary Sertoli Cells through Regulating Cep55/NF-kappa B/PI3K/Akt/FOX01/TNF-alpha Pathway. International Journal of Molecular Sciences, 2019.

Effect of heat treatment on the anti-tumor activity of lactoferrin in human colon tumor (HT29) model. Journal of Agricultural and Food Chemistry, 2019.

Toxicology studies of furosine in vitro/in vivo and exploration of the related mechanism. Toxicology Letters, 2018.

The toxic effects of aflatoxin B1 and aflatoxin M1 on kidney through regulating L-proline and downstream apoptosis. Biomed Research International, 2018.

Furosine induced apoptosis by the regulation of STAT1/STAT2 and UBA7/UBE2L6 genes in HepG2 cells. International Journal of Molecular Sciences, 2018.

Lactoferrin exerts anti-tumor effects by inhibiting angiogenesis in a HT29 human colon tumor model. Journal of Agricultural and Food Chemistry, 2017.